Structural Basis of Biological NO Generation by Octaheme Oxidoreductases

Structural basis of biological NO generation by octaheme oxidoreductases.

Nitric oxide is an important molecule in all domains of life with significant biological functions in both pro- and eukaryotes. Anaerobic ammonium-oxidizing (anammox) bacteria that contribute substantially to the release of fixed nitrogen into the atmosphere use the oxidizing power of NO to activate inert ammonium into hydrazine (N2H4). Here, we describe an enzyme from the anammox bacterium Kue...

Structural Basis of Biological NO Generation by

Structural basis of biological and immunological activity of parathyroid hormone.

4 Ibid., 50, 664 (1963). 6 Geiduschek, E. P., G. P. Tocchini-Valentini, and M. Sarnat, these PROCEEDINGS, 52, 486 (1964). 6 Green, M., these PROCEEDINGS, 52, 1388 (1964). 7Luria, S. E., Biochem. Biophys. Res. Commun., 18, 735 (1965). 8 Chandler, B., M. Hayashi, M. N. Hayashi, and S. Spiegelman, Science, 143, 47 (1964). 6Jansz, H. S., and P. H. Pouwels, Biochem. Biophys. Res. Commun., 18, 589 (1...

Structural basis for the biological activities of bovine seminal ribonuclease.

Bovine seminal ribonuclease (BS-RNase) is a homolog of RNase A with special biological properties that include specific antitumor, aspermatogenic, and immuno-suppressive activities. Unlike RNase A, BS-RNase is a dimer cross-linked by disulfide bonds between Cys31 of one subunit and Cys32 of the other. At equilibrium, this dimer is a mixture of two distinct quaternary forms, M = M and M x M. The...

Biological Rhythms Workshop IA: molecular basis of rhythms generation.

Current circadian models are based on genetic, biochemical, and structural data that, when combined, provide a comprehensive picture of the molecular basis for rhythms generation. These models describe three basic elements-input pathways, oscillator, and output pathways-to which each molecular component is assigned. The lines between these elements are often blurred because some proteins functi...